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Education:

  • PhD - University of Pittsburgh

  • MS - University of Pittsburgh

  • BA - Williams College

Department of Psychiatry and Behavioral Neuroscience
University of Chicago
5841 South Maryland Avenue, Chicago, IL 60637

About

Dr. Kate Keenan received a B.A. from Williams College in 1986, and a Ph.D. in Clinical Psychology from the University of Pittsburgh in 1995. She completed her clinical internship at the Children’s Memorial Hospital at Northwestern University and then joined the Department of Psychiatry at the University of Chicago, where she is currently Professor of Psychiatry and Behavioral Neuroscience.

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Research Interests

Dr. Keenan’s program of research in developmental psychopathology spans several developmental periods and phenotypes. The integrative thread running through each study is the aim of identifying the earliest appearing individual differences that connote risk for poor health, and the factors that are associated with the transition from risk to the dysfunction and impairment. The work is designed to be relevant to the understanding of causal mechanisms and to the development of prevention interventions. She is specifically interested in the study of the type and timing of stress exposure on health.

Dr. Keenan collaborated with Drs. Rolf Loeber and Magda Stouthamer-Loeber on the initial conceptualization, funding, and launching of the Pittsburgh Girls Study. She has directed several substudies to the PGS including the Pittsburgh Girls Emotions Study (PGS-E) and the The PGS-Health, Emotions, and Adaptation over Time (HEArT) study. Dr. Keenan’s research is funded through the National Institute of Mental Health, the National Institute of Heart Lung and Blood, the Eunice Kennedy Shriver National Institute of Child Health and Human Development, and the Office of the Director at NIH. She is past-President of the International Society for Research in Child and Adolescent Psychopathology.

Additional support comes from the University of Chicago Institute for Translational Medicine, Clinical and Translation Science Institute at the University of Pittsburgh, and the March of Dimes.

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Representative Publications​

  1. Keenan, K., Bartlett, T.Q., Nijland, M., Rodriquez, J., Nathanielsz, P., & Zurcher, N. (2013). Poor nutrition during pregnancy and lactation negatively impacts neurodevelopment of the offspring: Evidence from a translational primate model. American Journal of Clinical Nutrition, 98, 396-402. PMCID: PMC3712549. 

  2. Keenan, K., Hipwell, A.E., Babinski, D.E., Bortner, J., Henneberger, A., Hinze, A.E., Klostermann, S., Rischall, M., & Sapotichne, B. (2013). Examining the developmental interface of cortisol and depression symptoms in young adolescent girls. Psychoneuroendocrinology, 38, 2291-2299. PMCID: PMC3776001

  3. Keenan, K., Hipwell, A.E., Stepp, S.D., & Wroblewski, K. (2014). Testing an equifinality model of non-suicidal self-injury among early adolescent girls. Development and Psychopathology, 26, 851-862.

  4. Keenan, K., Culbert, K., Grimm, K.J., Hipwell, A.E., & Stepp, S.D. (2014). Timing and tempo: Exploring the complex association between pubertal development and depression in African American and European American girls. Journal of Abnormal Psychology, 123, 725-736. PMCID: PMC4227930

  5. Keenan, K., & Hipwell, A.E. (2015). Modulation of prenatal stress via docosahexaenoic acid supplementation: Implications for child mental health. Nutrition Reviews, 73, 166-174.

  6. Keenan, K., Hipwell, A.E., McAloon, R., Hoffmann, A., Mohanty, A., & Magee, K. (2016). The effect of prenatal fatty acid supplementation on infant outcomes in African American women living in low-income environments: A randomized, controlled trial. Psychoneuroendocrinology, 71, 170-175.

  7. Keenan, K., Hipwell, A.E., McAloon, R., Hoffmann, A., Mohanty, A., & Magee, K. (2017). Correspondence between maternal recall of birth complications and data from obstetrical records. Early Human Development, 105, 11-15.

  8. Keenan, K., Wroblewski, K., Matthews, A.K., Hipwell, A.E., & Stepp, S.D. (2018). Differences in childhood body mass index between lesbian/gay and bisexual and heterosexual female adolescents: A follow-back study. PLOS One. https://doi.org/10.1371/journal.pone.0196327

  9. Keenan, K., Hipwell, A.E., Class, Q.A., & Mbayiwa, K. (2018). Extending the developmental origins of disease model: Impact of preconception stress exposure on offspring neurodevelopment. Developmental Psychobiology, 60, 753-764.

  10. Keenan K, Berona J, Stepp SD, Hipwell AE Romito, M. (2021). Validity of the Trier Social Stress Test in studying discrimination stress. Stress, 24, 113-119.

  11. Keenan K, Fu H, Berona J, Tung I, Krafty R, Stepp SD, Hipwell AE (2021). Capturing the dynamic nature of stress exposure in the Pittsburgh Girls Study. Social Science Medicine – Population Health, 16.

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